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化学诱导的原发性肿瘤(Primary Tumor Models induced by Chemicals)

Tumor type

舌癌(Tongue cancer)

肝癌(Liver cancer)

食管癌(Esophageal cancer)

 结肠癌(Colon cancer)

Animals

4 weeks old F344 rat

4 weeks old BALB/C mouse

6 weeks old Wistar Rat

6 weeks old BALB/C mouse

Methods

Induced by 4NQO drinking

Induced by DEN drinking

Subcutaneous injection of NMBA with 5mg/kg weekly, for 16 weeks   

Intraperitoneal injection AOM with10mg/kg, then 2% DSS drinking for 7 days, followed by 14days normal drinking, 21days as a cycle, totally 4cycles

Time for tumor growth

18 weeks

16~20 weeks

16~20weeks

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化学诱导的原发性肿瘤(Primary Tumor Models induced by Chemicals)

化学诱导的原发性肿瘤(Primary Tumor Models induced by Chemicals)

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