Tumor type |
舌癌(Tongue cancer) |
肝癌(Liver cancer) |
食管癌(Esophageal cancer) |
结肠癌(Colon cancer) |
Animals |
4 weeks old F344 rat |
4 weeks old BALB/C mouse |
6 weeks old Wistar Rat |
6 weeks old BALB/C mouse |
Methods |
Induced by 4NQO drinking |
Induced by DEN drinking |
Subcutaneous injection of NMBA with 5mg/kg weekly, for 16 weeks |
Intraperitoneal injection AOM with10mg/kg, then 2% DSS drinking for 7 days, followed by 14days normal drinking, 21days as a cycle, totally 4cycles |
Time for tumor growth |
18 weeks |
16~20 weeks |
16~20weeks |
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